Hatzios Lab Publications at Yale:

11. Baskerville MJ, Kovalyova Y, Mejías-Luque R,  Gerhard M, and Hatzios SK. (2023) “Isotope tracing reveals bacterial catabolism of host-derived glutathione during Helicobacter pylori infection,” PLoS Pathog 19(7): e1011526.

10. Hatzios SK. (2023) “Moonlighting in the membrane,” Nat Chem Biol 19: 1436-1437.

9. Dumitrescu DG and Hatzios SK. (2023) “Emerging roles of low-molecular-weight thiols at the host–microbe interface,” Curr Opin Chem Bio 75: 102322.

8. Ramanathan R and Hatzios SK. (2023) “Activity-based tools for interrogating host biology during infection,” Isr J Chem 63: e202200095.

7. Dumitrescu DG, Gordon EM*, Kovalyova Y*, Seminara AB, Duncan-Lowey B, Forster ER, Zhou W, Booth CJ, Shen A, Kranzusch PJ, and Hatzios SK. (2022) “A microbial transporter of the dietary antioxidant ergothioneine,” Cell 185(24): 4526-4540.e18. (*equal contribution)

Featured in the following commentary: Nielsen J (2022) “Bioactive metabolites: The double-edged sword in your food,” Cell 185(24): 4469-4471.

6. DeColli AA, Koolik IM, Seminara AB, and Hatzios SK. (2022) “A propeptide-based biosensor for the selective detection of Vibrio cholerae using an environment-sensitive fluorophore,” Cell Chem Biol 29: 1505-1516.e7.

5. Kovalyova Y, Bak DW, Gordon EM, Fung C, Shuman JHB, Cover TL, Amieva MR, Weerapana E, and Hatzios SK. (2022) “An infection-induced oxidation site regulates legumain processing and tumor growth,” Nat Chem Biol 18: 698-705. Also on bioRxiv (2021). 

Featured in the following commentary: Yang J (2022) “Oxidize me to the space,” Nat Chem Biol 18: 680-681.

4. Gordon EM and Hatzios SK. (2020) “Chemical tools for decoding redox signaling at the host-microbe interface,” PLoS Pathog 16(12): e1009070.

3. Howell M*, Dumitrescu DG*, Blankenship LR, Herkert D, and Hatzios SK. (2019) “Functional characterization of a subtilisin-like serine protease from Vibrio cholerae,” J Biol Chem 294: 9888-9900. (*equal contribution)

2. Kovalyova Y and Hatzios SK. (2019) “Activity-based protein profiling at the host-pathogen interface,” Curr Top Microbiol Immunol 420: 73-91.

1. Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang K, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, and Zhang DD. (2017) “Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease,” Cell 171: 273-285.


Stavroula’s Pre-Yale Publications:

9. Hatzios SK, Abel S, Martell J, Hubbard T, Sasabe J, Munera D, Clark L, Bachovchin DA, Qadri F, Ryan ET, Davis BM, Weerapana E, and Waldor MK. (2016) Chemoproteomic profiling of host and pathogen enzymes active in cholera,” Nat Chem Biol 12: 268-274.

Featured on the cover and in this Nature Chemical Biology commentary.

8. Wampande EM, Hatzios SK, Achan B, Mupere E, Nsereko M, Mayanja HK, Eisenach K, Boom WH, Gagneux S, and Joloba ML. (2015) “A single-nucleotide-polymorphism real-time PCR assay for genotyping of Mycobacterium tuberculosis complex in peri-urban Kampala,” BMC Infect Dis 15: 396.

7. Munera D, Ritchie JM, Hatzios SK, Bronson R, Fang G, Schadt EE, Davis BM, and Waldor MK. (2014) “Autotransporters but not pAA are critical for rabbit colonization by shiga toxin-producing Escherichia coli O104:H4,” Nat Commun 5: 3080.

6. Hatzios SK, Baer CE, Rustad TR, Siegrist MS, Pang JM, Ortega C, Alber T, Grundner C, Sherman DR, and Bertozzi CR. (2013) “Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase,” Proc Natl Acad Sci USA 110(52): E5069-77.

5. Hatzios SK, Ringgaard S, Davis BM, and Waldor MK. (2012) “Studies of dynamic protein-protein interactions in bacteria using Renilla luciferase complementation are undermined by nonspecific enzyme inhibition,” PLoS ONE 7(8): e43175.

4. Hatzios SK and Bertozzi CR. (2011) “The regulation of sulfur metabolism in Mycobacterium tuberculosis.” PLoS Pathog 7(7): e1002036.

3. Hatzios SK, Schelle MW, Newton GL, Sogi KM, Holsclaw CM, Fahey RC, and Bertozzi CR. (2011) “The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth,” Bioorg Med Chem Lett 21(17): 4956-4959.

2. Hatzios SK, Schelle MW, Holsclaw CM, Behrens CR, Botyanszki Z, Lin FL, Carlson BL, Kumar P, Leary JA, and Bertozzi CR. (2009) “PapA3 is an acyltransferase required for Polyacyltrehalose biosynthesis in Mycobacterium tuberculosis.” J Biol Chem 284: 12745-12751.

1. Hatzios SK, Iavarone AT, and Bertozzi CR. (2008) “Rv2131c from Mycobacterium tuberculosis is a CysQ 3’-phosphoadenosine-5’-phosphatase.” Biochemistry 47: 5823-5831.